I ran into the following issue with a vCenter database. The DB had grown 25GB within a week. The vpx_event and vpx_even_arg tables were the primary growth contributors. When reviewing the Events side of the Tasks & Events tab in the vCenter console, there were a very high volume of logon and logoff events (3 per second). These events were all being created by a single antivirus scan VM, which was then rebuilt. After resolving the source of events, the database growth went negative.